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Table 2 Clinical characteristics of patients stratified by tranexamic acid administration. Continuous variables expressed as mean ± standard deviation

From: Outcomes of tranexamic acid administration in military trauma patients with intracranial hemorrhage: a cohort study

 Total (n = 71)TXA (n = 14)No TXA (n = 57)P-value
Age, y25.2 ± 4.924.2 ± 3.125.5 ± 5.30.64
ISS28.2 ± 12.336.6 ± 12.526.2 ± 11.40.003*
Penetrating TBI, n36 (50.7%)6 (42.3%)30 (52.6%)0.56
Blast injury, n57 (80.3%)12 (85.7%)45 (80.0%)0.72
Gunshot wound, n13 (18.3%)2 (14.3%)11 (19.3%)0.72
Received massive transfusion within 24 h, n9 (12.7%)4 (28.6%)5 (8.8%)0.07
Platelets < 100 (×109/L), n7 (9.9%)3 (21.4%)4 (7.0%)0.13
INR > 1.5, n14 (19.7%)7 (50.0%)7 (12.3%)0.004*
Lower extremity amputation, n6 (8.5%)5 (35.7%)1 (1.8%)< 0.001*
Pelvic fracture, n3 (4.2%)1 (7.1%)2 (3.5%)0.5
Chest AIS 3+, n17 (23.9%)6 (42.3%)11 (19.3%)0.2
Abdomen AIS 3+, n8 (11.3%)3 (21.4%)5 (8.8%)0.19
Extremity AIS 3+, n19 (26.8%)8 (57.1%)11 (19.3%)0.008*
Type of ICH
Epidural, n8 (11.3%)3 (21.4%)5 (8.8%)0.19
Subdural, n33 (46.5%)6 (42.3%)27 (47.4%)1.00
Intraparenchymal, n57 (80.3%)14 (100%)43 (75.4%)0.06
Subarachnoid, n43 (60.6%)8 (57.1%)35 (61.4%)0.77
Intraventricular, n18 (25.3%)6 (42.9%)12 (21.1%)0.17
Presence of DAI, n7 (9.9%)2 (14.3%)5 (8.8%)0.62