Table 3 The putative associations between intramuscular naloxone dose (0.4 mg vs. 0.8 mg) and sex, age, vital signs and place of attendance (n = 1530), Model 1
From: Prehospital naloxone administration – what influences choice of dose and route of administration?
0.4 mg 100% (n = 657) | 0.8 mg 100% (n = 873) | Unadjusted OR (95% CI) | Adjusted OR (95% CI) | |
|---|---|---|---|---|
Sex | ||||
Women | 30.8 (202) | 18.6 (162) | ref | ref |
Men | 69.3 (455) | 81.4 (711) | 2.0*** [1.5, 2.5] | 2.2*** [1.7, 2.9] |
Age (years) | ||||
< 30 | 24.2 (159) | 23.1 (202) | ref | ref |
30–49 | 58.5 (384) | 59.7 (521) | 1.1 [0.8, 1.4] | 1.2 [0.9, 1.5] |
≥ 50 | 17.4 (114) | 17.2 (150) | 1.0 [0.7, 1.5] | 1.3 [0.9, 1.8] |
Glasgow Coma Scale | ||||
3/15 | 27.7 (182) | 56.5 (493) | 9.1*** [5.2, 16.2] | 7.1*** [3.8, 13.1] |
4–9/15 | 21.6 (142) | 19.8 (173) | 4.1*** [2.2, 7.5] | 4.0*** [2.1, 7.5] |
10–14/15 | 33.8 (222) | 13.8 (120) | 1.8* [1.0, 3.2] | 1.8 [1.0, 3.2] |
15/15 | 8.2 (54) | 1.8 (16) | ref | ref |
No valid report | 8.7 (57) | 8.1 (71) | 4.2*** [2.2, 8.0] | 3.8*** [2.0, 7.4] |
Respiration rate | ||||
0/min | 7.2 (47) | 20.6 (180) | 5.1*** [3.5, 7.6] | 3.4*** [2.2, 5.3] |
1–8/min | 35.5 (233) | 43.0 (375) | 2.2*** [1.7, 2.7] | 1.7*** [1.3, 2.2] |
≥ 9/min | 44.9 (295) | 25.2 (220) | ref | ref |
No valid report | 12.5 (82) | 11.2 (98) | 1.6** [1.1, 2.3] | 1.6* [1.1, 2.3] |
Place of attendance | ||||
Safe injection facility | 41.1 (270) | 37.5 (327) | 0.9 [0.7, 1.1] | 0.6*** [0.5, 0.8] |
All other locations | 58.9 (387) | 62.5 (546) | ref | ref |