Skip to main content

Table 2 Comparison of clinical and etiological findings in sepsis patients

From: A retrospective study of sepsis-associated encephalopathy: epidemiology, clinical features and adverse outcomes

 

All patients

n = 291

SAE

n = 127

non-SAE

n = 164

P

Disease type n (%)

 Medical disease

198 (68.0)

88 (69.3)

110 (67.1)

0.358

 Emergency surgery

47 (16.2)

23 (18.1)

24 (14.6)

 Elective surgery

46 (15.8)

16 (12.6)

30 (18.3)

Infection sites n (%)

 Respiratory tract

159 (54.6)

76 (59.8)

83 (50.6)

0.076

 Biliary tract

25 (8.6)

8 (6.3)

17 (10.4)

0.220

 Gastrointestinal tract

59 (20.3)

34 (26.8)

25 (15.2)

0.015**

 Urinary tract

16 (5.5)

9 (7.1)

7 (4.3)

0.296

 Bloodstream

14 (4.8)

7 (5.5)

7 (4.3)

0.623

 Skin and soft tissue

15 (5.2)

5 (3.9)

10 (6.1)

0.408

Detected pathogens n (%)

 Staphylococcus

35 (12.3)

16 (12.6)

19 (11.6)

0.792

 Enterococcus

34 (15.5)

21 (16.5)

13 (7.9)

0.023*

Escherichia coli

67 (30.6)

31 (24.4)

36 (21.9)

0.621

 Acinetobacter

61 (20.9)

27 (21.3)

34 (20.7)

0.913

 Pseudomonas

18 (6.2)

8 (6.3)

10 (6.1)

0.944

 Klebsiella

27 (9.3)

11 (8.7)

16 (9.8)

0.750

 Fungus

32 (10.9)

13 (10.2)

19 (11.6)

0.715

 Others

15 (5.2)

6 (4.7)

9 (5.5)

0.770

Biochemical Indexes (median)

 PCT (μg/L)

1.89 [0.66,5.37]

2.33 [1.14, 6.97]

1.39 [0.42, 3.99]

< 0.01*

 Endotoxin (EU/mL)

0.11 [0.05, 0.20]

0.12 [0.05, 0.21]

0.10 [0.05, 0.19]

0.464

 WBC (×109/L)

10.8 [7.60, 15.8]

10.9 [8.5, 16.2]

11.35 [7.70, 15.88]

0.245

 PLT (×109/L)

152 [76.7, 191.5]

105 [56.0, 180.0]

168 [110.0, 246.5]

< 0.01*

 HCT

30.1 [27.0, 33.0]

20.3 [18.1, 22.1]

33.4 [33.0, 34.3]

0.069

 Cr (μmol/L)

78 [52.0, 95.8]

78 [59.0, 109.8]

73.5 [51.5, 87.0]

0.315

  1. SAE sepsis-associated encephalopathy, PCT procalcitonin, WBC white blood cell, PLT blood platelet, HCT hematocrit, Cr serum creatinine
  2. *Statistical analysis using Mann Whitney test, **Statistical analysis using Fisher’s exact probability method