SARS-CoV-2 positive (n = 39) | SARS-CoV-2 negative (n = 96) | p-value | |
---|---|---|---|
patient characteristics | |||
age [years] | 61 ± 16 (25–84) a | 60 ± 18 (18–95) a | 0.774 c |
sex [male] | 22 (56.4%) b | 51 (53.1%) b | 0.728 d |
BMI [kg/m2] | 26.3 ± 6.6 (15.8–52.5) a | 26.3 ± 6.2 (16.4–46.9) a | 0.722 c |
vital sign on admission | |||
MAD [mmHg] | 101,4 ± 14 (71–145) a | 98.3 ± 16.6 (58–133) a | 0.361 c |
heart rate [/min] | 84.8 ± 16.6 (42–113) a | 94.8 ± 22 (42–148) a | 0.034 c |
temperature [°C] | 37.7 ± 0.9 (36.0–39.4) a | 37.5 ± 1.0 (35.0–40.1) a | 0.101 c |
symptoms at admission | |||
fever | 30 (23.1%) b | 44 (45.8%) b | 0.001 d |
cough | 26 (66.7%) b | 35 (36.5%) b | 0.003 d |
dyspnea | 25 (64.1%) b | 57 (59.4%) b | 0.610 d |
chest pain | 6 (15.4%) b | 19 (19.8%) b | 0.550 d |
limb pain | 8 (20.5%) b | 4 (4.2%) b | 0.002 d |
gastrointestinal symptoms | 11 (28.2%) b | 22 (22.9%) b | 0.517 d |
medical history | |||
hypertension | 19 (48.7%) b | 43 (44.8%) b | 0.678 d |
chronic heart failure | 3 (7.7%) b | 13 (13.5%) b | 0.341 d |
diabetes | 5 (12.8%) b | 17 (17.7%) b | 0.611 d |
chronic kidney injury | 2 (5.1%) b | 19 (19.8%) b | 0.037 d |
oncological disease | 7 (17.9%) b | 35 (36.5%) b | 0.035 d |
lung disease | 4 (10.3%) b | 33 (34.4%) b | 0.005 d |
smoking (ongoing/ previous) | 3 (7.7%) b | 22 (22.9%) b | 0.050 d |
laboratory results at admission | |||
leukocyte count (tsd/μl) (n = 135) | 6.96 ± 4.71 (1.05–26.80)a | 10.57 ± 7.13 (0.44–49.71) a | < 0.001 c |
platelet count (tsd/μl) (n = 135) | 189.46 ± 88.04 (10.00–490.00) a | 245.05 ± 124.92 (8.00–699.00) a | 0.010 c |
hemoglobin g/dl (n = 135) | 13.03 ± 1.98 (8.80–17.10) a | 11.91 ± 2.49 (4.38–16.40) a | 0.003 c |
creatinine mg/dl (n = 135) | 1.09 ± 0.66 (0.37–4.18) a | 1.31 ± 1.31 (0.49–10.50) a | 0.627 c |
C-reaktive protein mg/l (n = 135) | 71.1 ± 77.1 (3.0–291.9) a | 69.6 ± 82.9 (3.0–374.3) a | 0.571 c |
procalcitonin ng/ml (n = 129) | 0.16 ± 0.21 (0.05–0.95) a | 1.67 ± 8.55 (0.05–81.60) a | 0.223 c |
lactat dehydrogenase U/l (n = 135) | 369 ± 216 (141–1108) a | 285 ± 155 (137–1163) a | 0.006 c |
proBNP (ng/l) (n = 127) | 1296 ± 666 (50–18,995) a | 3004 ± 832 (50–5733) a | 0.085 c |
d-dimer (mg/l) (n = 98) | 3.53 ± 1.55 (0.19–35.20)a | 2.17 ± 0.45 (0.19–21.57) a | 0.945 c |
inpatient care | |||
hospital admission | 33 (84.6%) b | 65 (67.7%) b | 0.046 d |
ICU admission | 5 (12.8%) b | 11 (11.5%) b | 0.777 d |
death | 6 (15.4%) b | 6 (6.3%) b | 0.104 d |