Skip to main content

Table 2 Factors associated with positive blood culture in patients suspected of infection presenting at the emergency department

From: Clinical factors associated with bloodstream infection at the emergency department

Factors

Unadjusted Odds Ratio (95% CI)

aAdjusted Odds Ratio (95% CI)

p-value

Comorbid conditions

 Age > 55

1.54 (1.30–1.81)

1.33 (1.04–1.72)

0.02

 Sex

0.84 (0.73–0.99)

0.94 (78.1–1.13)

0.52

 Emergency severity index level

0.62 (0.55–0.70)

0.87 (0.71–1.13)

0.18

 CCI

1.13 (1.09–1.06)

0.98 (0.92–1.04)

0.46

 Liver disease

2.24 (1.87–2.67)

2.04 (1.59–2.61)

< 0.01

 Diabetes mellitus

1.36 (1.15–1.62)

1.08 (0.89–1.30)

0.45

 Moderate to severe CKD

1.63 (1.28–2.08)

1.68 (1.22–2.32)

0.01

 Solid organ tumor

1.59 (1.35–1.87)

1.40 (1.09–1.80)

0.01

 Hypertension

1.34 (1.13–1.57)

1.14 (0.92–1.41)

0.24

On arrival parameter

 History of Chills

2.67 (2.12–3.38)

1.94 (1.43–2.62)

< 0.01

 Temperature > 38.3 °C

1.40 (1.32–1.50)

1.77 (1.39–2.25)

< 0.01

 Heart rate > 120 /min

1.01 (1.00–1.01)

0.96 (0.73–1.26)

0.76

 SBP < 90 or MAP < 65

2.01 (1.59–2.54)

1.22 (0.86–1.71)

0.26

 Respiratory rate > 22/min

1.03 (1.02–1.04)

0.89 (0.71–1.26)

0.32

 SIRS criteria ≥2

2.5 (2.03–3.20)

1.21 (0.94–1.53)

0.26

 qSOFA criteria ≥2

1.79 (1.49–2.15)

1.20 (0.94–1.53)

0.15

 NEWS ≥7

1.73 (1.47–2.04)

0.93 (0.73–1.18)

0.53

Beyond first hour parameter

bLactate level

1.13 (1.10–1.16)

1.10 (1.07–1.14)

< 0.01

 WBC > 11,000 /microliter

1.31 (1.12–1.52)

1.28 (1.03–1.59)

0.03

 WBC < 3000 /microliter

2.30 (1.70–3.13)

2.48 (1.68–3.66)

< 0.01

  1. CCI Charlson Comorbidity Index, CKD chronic kidney disease, SBP systolic blood pressure, MAP mean arterial pressure, SIRS Systemic Inflammatory Response Syndrome; qSOFA quick Sepsis-related Organ Failure Assessment, NEWS National Early Warning Score, WBC white blood cell
  2. a adjusted by the studied factors shown in this table
  3. b initial lactate level in mmol/L.