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Table 2 key diagnostics and evidence-based medications within the first 24 h and in-hospital outcomes based on ACS subtypes

From: Management quality indicators and in-hospital mortality among acute coronary syndrome patients admitted to tertiary hospitals in Ethiopia: prospective observational study

Diagnostics and Medications

All patients

n = 181

STEMI

n = 111

NSTE-ACS n = 70

P value

Key diagnostics

ECG within 12 h

154 (79.6)

90 (81.1)

54 (77.1)

0.522

Positive cardiac biomarker

161 (89.0)

111 (100.0)

50 (71.4)

< 0.001*

Diagnostic Angiography

79 (43.6)

52 (46.8)

27 (38.6)

0.274

Echocardiography

174 (96.1)

107 (96.4)

64 (95.7)

0.817

LVEF <40%

70 (38.7)

42 (37.8)

28 (40.0)

0.771

In-hospital medications within 24 h

Aspirin

140 (77.3)

92 (82.8)

48 (68.6)

0.025*

Clopidogrel

132 (72.9)

88 (79.3)

44 (62.8)

0.015*

Dual antiplatelet

132 (72.9)

88 (79.3)

44 (62.8)

0.015*

Beta-blocker (n = 147)

141 (67.2)

80 (72.7)

41 (58.6)

0.023*

Any heparin

111 (61.3)

73 (65.8)

38 (54.3)

0.122

Statin

135 (74.6)

90 (81.1)

45 (64.3)

0.011*

ACEI/ARBs (n = 132)

111 (61.3)

73 (65.8)

38 (54.3)

0.449

All GDMTa

103 (56.9)

71 (64.0)

32 (45.7)

0.016

In-hospital reperfusion therapy

Thrombolysis n (%)

0 (0)

0 (0)

0 (0)

–

PCI n (%)

13 (7.2)

10 (9)

3 (3.4)

0.231

In-hospital events

Mortality

37 (20.4)

29 (26.1)

8 (11.4)

0.017

Cardiogenic shock

16 (8.8)

13 (11.7)

3 (4.3)

0.043*

Stroke

5 (2.8)

3 (2.7)

2 (2.9)

0.951

Re-infraction

10 (5.5)

7 (6.3)

3 (4.3)

0.562

Major bleeding

7 (3.9)

4 (3.6)

3 (4.3)

0.818

Heart failure

18 (10.0)

13 (11.7)

5 (7.0)

0.317

Non-fatal MACE

45 (25.0)

31 (28.0)

14 (20.0)

0.299

Acute kidney injury

22 (12.2)

13 (11.7)

9 (12.9)

0.818

Atrial fibrillation

13 (7.2)

7 (6.3)

6 (8.6)

0.565

Hospital acquired infection

16 (8.8)

10 (9.0)

6 (8.6)

0.920

  1. ACEI Angiotensin-converting enzyme inhibitor, ARB Angiotensin-receptor blockers, ECG Electrocardiography, GDMT Guideline-directed medical therapy, LVEF Left ventricular ejection fraction, MACE Major adverse cardiovascular events, NSTE-ACS Non-ST-elevation acute coronary syndrome, PCI Percutaneous coronary intervention, STEMI ST-elevation myocardial infarction
  2. aGDMT: patients who received aspirin, clopidogrel, beta-blocker and ACEI within 24 h; *statistically significant at p < 0.05