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Table 1 Characteristics of Training ang Testing sets

From: A machine learning model to predict critical care outcomes in patient with chest pain visiting the emergency department

Features

Training set N = 338, N(%)/M (IQR)

Testing set N = 145, N(%)/M (IQR)

Z/χ2

P values

Age, yearsb

64 (53–73)

66 (53–74.5)

0.984

0.352

Critical care outcomes

153 (45.3)

66 (45.5)

< 0.001

0.959

Male

261 (77.2)

112 (77.2)

< 0.001

0.996

Mode of arrival

 Ambulance use

22 (6.5)

9 (6.2)

3.37

0.498

 Transfer from other hospital

44 (13.0)

24 (16.5)

  

 Walk in

268 (79.3)

108 (74.5)

  

 Intra-hospital transfer

2 (0.6)

1 (0.7)

  

 Others

2 (0.6)

3 (2.1)

  

Historya

9 (2.7)

1 (0.7)

1.948

0.163

Diabetes

94 (27.8)

37 (25.5)

0.27

0.603

Hypertension

193 (57.1)

86 (59.3)

0.203

0.652

Dyslipidemia

103 (30.5)

45 (31.0)

0.015

0.902

Smoking

144 (42.6)

55 (37.9)

0.914

0.339

Obesitya

4 (1.2)

2 (1.4)

0.032

0.859

Number of risk factorsa

 0

47 (13.9)

25 (17.2)

1.58

0.812

 1

110 (32.5)

49 (33.8)

  

 2

119 (35.2)

44 (30.3)

  

 3

54 (16.0)

23 (15.9)

  

 4

8 (2.4)

4 (2.8)

  

Acute heart failure

37 (10.9)

11 (7.6)

1.28

0.258

Type of chest pain

 Only atypical symptoms

39 (11.5)

17 (11.7)

0.429

0.807

 Typical and atypical symptoms

100 (29.6)

47 (32.4)

  

 Only typical symptoms

199 (58.9)

81 (55.9)

  

Duration of chest painb

 <24 h

209 (61.8)

94 (64.8)

0.718

0.698

 24 h-7d

80 (23.7)

34 (23.4)

  

 >7d

49 (14.5)

17 (11.7)

  

Electrocardiogram findings

 Normal

68 (20.1)

28 (19.3)

0.048

0.976

 Nonspecific abnormalities

135 (39.9)

58 (40.0)

  

 Ischemia

135 (39.9)

59 (40.7)

  

Killip class

 I

203 (60.1)

93 (64.1)

0.983

0.805

 II

68 (20.1)

24 (16.6)

  

 III

23 (6.8)

10 (6.9)

  

 IV

44 (13.0)

18 (12.4)

  

Reperfusion therapyb

 PCI

90 (26.6)

49 (33.8)

2.585

0.275

 CABG

2 (0.6)

1 (0.7)

  

 None

246 (72.8)

95 (65.5)

  

Temperaturea, °C

 36.0 ≤ T ≤ 38.0

324 (95.9)

143 (98.6)

2.418

0.12

  < 36.0 or > 38.0

14 (4.1)

2 (1.4)

  

Heart rate, beats/min

 60–100

232 (68.6)

114 (78.6)

4.976

0.026

  < 60 or > 100

106 (31.4)

31 (21.4)

  

Respiratory rate, beats/min

 11–20

196 (58.0)

81 (55.9)

0.188

0.665

  ≤ 10 or > 20

142 (42.0)

64 (44.1)

  

Systolic pressureb, mmHg

  ≥ 90

308 (91.1)

137 (94.5)

1.579

0.209

  < 90

30 (8.9)

8 (5.5)

  

Diastolic pressure, mmHg

  ≥ 60

286 (84.6)

130 (89.7)

2.157

0.142

  < 60

52 (15.4)

15 (10.3)

  

Conscious stateb

 Alert

336 (99.4)

143 (98.6)

0.766

0.381

SCr b, μmol/L

  < 186

322 (95.3)

138 (95.2)

1.383

0.501

 186–451

11 (3.3)

3 (2.1)

  

 >451

5 (1.5)

4 (2.8)

  

cTnI, μg/L

  < 0.2

82 (24.3)

35 (24.1)

3.753

0.153

 0.2–10.0

225 (66.6)

104 (71.7)

  

  > 10.0

31 (9.2)

6 (4.1)

  

CKMBb, U/L

28.5 (11 ~ 101.5)

22 (12 ~ 59)

−0.894

0.371

NT-proBNPb, ng/L

1539.69 (485.25 ~ 3618.75)

1539.69 (305.85 ~ 3349)

−0.809

0.419

CKb, U/L

310 (95 ~ 910.5)

190 (78.5 ~ 491)

−2.186

0.029

  1. PCI percutaneous transluminal coronary intervention, CABG coronary artery bypass grafting, SCr serum creatinine, cTnI cardiac troponin I, CKMB creatine kinase-MB, NT-proBNP N-terminal pro brain natriuretic peptide, CK creatine kinase
  2. aFisher’s test
  3. bWilcoxon’s test