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Table 3 Results of ROC analysis of dichotomized values in the prediction of sepsis

From: Monocyte distribution width (MDW) as a new tool for the prediction of sepsis in critically ill patients: a preliminary investigation in an intensive care unit

Test predictors

N (%)

pre-test probability

Sensitivity

(95% CI)

Specificity

(95% CI)

PPV

(95% CI)

NPV

(95% CI)

AUC

(95% CI)

MDW > 20.0

126 (97.7)

0.58

95.9 (88.5–99.1)

35.8 (23.1–50.2)

67.3 (57.4–76.2)

86.4 (65.1–97.1)

0.66 (0.59–0.73)

MDW > 22.0

126 (97.7)

0.58

79.5 (68.4–88.0)

71.7 (57.7–83.2)

79.5 (68.4–88.0)

71.7 (57.7–83.2)

0.76 (0.68–0.83)

MDW > 23.0

126 (97.7)

0.58

75.3 (63.9–84.7)

88.7 (77.0–95.7)

90.2 (79.8–96.3)

72.3 (59.8–82.7)

0.82 (0.75–0.89)

PCT > 1a

128 (99.2)

0.58

64.9 (52.9–75.6)

77.8 (64.4–88.0)

80.0 (67.7–89.2)

61.8 (49.2–73.3)

0.71 (0.63–0.79)

PCT > 0.5a

128 (99.2)

0.58

77.0 (65.8–86.0)

70.4 (56.4–82.0)

78.1 (66.9–86.9)

69.1 (55.2–80.9)

0.74 (0.66–0.82)

MDW > 20.0 and PCT > 0.5a

126 (97.7)

0.58

74.0 (62.4–83.5)

77.4 (63.8–87.7)

81.8 (70.4–90.2)

68.3 (55.0–79.7)

0.76 (0.68–0.83)

MDW > 22.0 and PCT > 0.5a

126 (97.7)

0.58

71.2 (59.4–81.2)

88.7 (77.0–95.7)

89.7 (78.8–96.1)

69.1 (56.7–79.8)

0.80 (0.73–0.87)

MDW > 23.0 and PCT > 0.5a

126 (97.7)

0.58

68.5 (56.6–78.9)

92.5 (81.8–97.9)

92.6 (82.1–97.9)

68.1 (56.0–78.6)

0.80 (0.74–0.87)

  1. PCT Procalcitonin, MDW Monocyte Distribution Width, PPV Positive Predictive Value, NPV Negative Predictive Value, aunit of measurement: ng/mL