Table 1 Baseline characteristics of the patients with and without clotting factor replacement
Characteristics | FFP group | Cryo group | FFP and cryo group | Control group | P value |
|---|---|---|---|---|---|
(n = 51) | (n = 15) | (n = 24) | (n = 33) |  | |
Age, year, (mean ± SD) | 48 ± 16.2 | 52 ± 16.7 | 52 ± 15.7 | 48 ± 18.4 | 0.774 |
Male sex, n (%) | 29/51 (56.9) | 8/15 (53.3) | 19/24 (79.2) | 19/33 (57.6) | 0.238 |
WBC, × 109/L, (mean ± SD) | 12.4 ± 4.4 | 13.4 ± 6.5 | 13.8 ± 6.6 | 12.0 ± 4.2 | 0.550 |
Hemoglobin, g/dL,(mean ± SD) | 139 ± 16.8 | 134 ± 28.7 | 132 ± 29.0 | 135 ± 18.4 | 0.621 |
Platelets, ×109/L,(mean ± SD) | 163.5 ± 75.1 | 156 ± 75.2 | 123 ± 62.3 | 167 ± 51.2 | 0.065 |
BUN, mmol/L, (mean ± SD) | 5.3 ± 1.9 | 5.1 ± 1.5 | 5.9 ± 2.9 | 4.8 ± 1.9 | 0.305 |
Creatinine, μmol/L, (mean ± SD) | 81.4 ± 22.8 | 70.4 ± 15.9 | 91.6 ± 37.1 | 79.3 ± 19.5 | 0.079 |
Serum potassium, mmol/L, (mean ± SD) | 3.6 ± 0.3 | 3.6 ± 0.4 | 3.7 ± 0.3 | 3.7 ± 0.4 | 0.468 |
D-dimer,ng/mL, (mean ± SD) | 858 ± 481.9 | 685 ± 381.0 | 837 ± 636.0 | 688 ± 520.0 | 0.486 |
Time of antivenom post-bite | 24/51 (47.1) | 10/15 (66.7) | 9/24 (37.5) | 22/33 (66.7) | 0.085 |
(≤6 h), n (%) |  |  |  |  |  |
Amount of antivenom,vial,(mean ± SD) | 2 ± 0.9 | 2 ± 1.2 | 2 ± 0.5 | 2 ± 0.8 | 0.348 |
Hours of clotting factor given after admission,hour,(mean ± SD) | 41 ± 38.2 | 36 ± 35.6 | 24 ± 34.0 | – | 0.269 |