Table 1 Baseline characteristics of the patients according to 90-day survival
Parameters | All patients n = 62 | Survivors n = 45 | Non-survivors n = 17 | p-Value |
|---|---|---|---|---|
Demographic characteristics | ||||
Female, n (%) | 24 (38.71) | 17 (37.78) | 7 (41.18) | 0.806 |
Age, y, mean (SD) | 60.50 (15.16) | 58.67 (14.92) | 65.35 (15.14) | 0.122 |
BMI, kg/m2, mean (SD) | 24.61 (3.95) | 24.97 (3.63) | 23.63 (4.68) | 0.236 |
Severity of illness | ||||
Septic shock, median days (IQR) | 1(0-6) | 0(0-3.5) | 4(1-15.5) | 0.000 |
PaO2/FiO2 ratio, mean (SD) | 212.56 (103.29) | 234.36 (99.39) | 154.88 (92.97) | 0.006 |
APACHE II score, mean (SD) | 12.23 (8.08) | 10.40 (6.94) | 17.06 (9.09) | 0.003 |
SOFA score, median (IQR) | 4.00(3.00-7.25) | 4.00(2.50-5.50) | 8.00(4.00-12.00) | 0.001 |
LIPS score, mean (SD) | 6.76 (3.05) | 5.78 (2.90) | 9.35 (1.60) | 0.000 |
Source of infection, n (%) | ||||
Pneumonia | 45(72.58) | 34(75.56) | 11(64.71) | 0.197 |
Non-pulmonary sepsis | 17(27.42) | 16(35.56) | 1(5.88) | 0.197 |
Pathogenic microorganisms, n (%) | ||||
Gram-positive bacteria | 5(8.06) | 4(8.89) | 1(5.88) | 1.000 |
Gram-negative bacteria | 33(53.23) | 25(55.56) | 8(47.06) | 0.550 |
Virus | 15(24.19) | 11(24.44) | 4(23.53) | 1.000 |
Others | 9(14.52) | 5(11.11) | 4(23.53) | 0.404 |
Inflammation indicators | ||||
C-reactive protein (mg/L), mean (SD) | 72.17 (66.50) | 63.56 (64.52) | 94.95 (68.18) | 0.098 |
Procalcitonin (ng/mL), median (IQR) | 0.77(0.20-3.11) | 0.61(0.11-4.92) | 1.63(0.69-2.74) | 0.124 |
Prescribed drugs | ||||
Hormone | 27(43.55) | 17(37.78) | 10(58.82) | 0.136 |
Mechanical ventilation, median days (IQR) | 7.00(0-18.25) | 4.00(0-14.00) | 18.00(7.00-39.00) | 0.002 |
Hospital duration, mean days (SD) | 26.19 (21.73) | 24.20 (12.70) | 31.47 (36.29) | 0.430 |