The following individuals acted as site study leads for PERUKI and/or GAPRUKI in their institution, as listed:
Adrian Boyle, Peter Heinz (Addenbrooke’s Hospital, Cambridge, England); Shrouk Messahel, Dan Hawcutt (Alder Hey Children’s Hospital NHS Foundation Trust, Liverpool, England); Caroline Ponmani (Barking, Havering & Redbridge University Hospitals NHS Trust, England); Chris Bird, Deepthi Jyothish (Birmingham Children’s Hospital, Birmingham, England); Catherine Williams (Bolton NHS Foundation Trust, Bolton, England); Ronan O’Sullivan (Bon Secours Hospital, Cork, Ireland); Elizabeth Jones (Bradford Royal Infirmary, Bradford, England); Mark Lyttle, Nwanneka Sargant (Bristol Royal Hospital for Children Bristol, England); James Ross (Chelsea & Westminster NHS Foundation Trust, London, England); Michael Barrett, Sinead Harty (Children’s Health Ireland at Crumlin, Dublin, Ireland); Turlough Bolger, David Coghlan (Children’s Health Ireland at Tallaght, Dublin, Ireland); Patrick Fitzpatrick, Conor Hensey (Children’s Health Ireland at Temple Street, Dublin, Ireland); Tim Hussan (County Durham & Darlington NHS Foundation Trust, England); Kate Charlick (Derriford Hospital, Plymouth, England); William Verling (Dorset County Hospital, Dorset, England); Peter Christian (East Kent Hospital, England); Matthew Clark (East Sussex NHS Health Trust, England); Bhavni Shah (Epsom General Hospital, Epsom, England); John Criddle, Ronny Cheung (The Evelina London Children’s Hospital, London, England); Roger Alcock (Forth Valley Hospital, Larbert, Scotland); Patrick Aldridge (Frimley Park Hospital, Frimley, England); Russell Peek (Gloucestershire Hospitals NHS Foundation Trust, Gloucester, England); Mark Anderson (Great North Children’s Hospital, Newcastle-upon-Tyne, England); Elizabeth Herrieven (Hull Royal Infirmary, Hull, England); Katherine Jerman, Arshid Murad (James Cook University Hospital, Middlesbrough, England); Charlotte Brown, Andy Marshall (John Radcliffe Hospital, Oxford, England); Fleur Cantle (Kings College Hospital, London, England); Gavin Wilson (Kingston Hospital NHS Foundation Trust, Kingston-upon-Thames, England); Alice Downes (Leeds General Infirmary, Leeds, England); Damian Roland, Srini Bandi (Leicester Royal Infirmary, Leicester, England); Adebayo Da-Costa (Medway Hospital NHS Foundation Trust, Gillingham, England); Ray Barry (Mercy University Hospital, Cork, Ireland); Natasha De Vere (The Mid Yorkshire Hospitals NHS Trust, England); Clare Dieppe (Morriston Hospital, Swansea, Wales); Jane Evans (Norfolk & Norwich University Hospital, Norwich, England); Gayle Hann, Clare Tipper (North Middlesex Hospital, London, England); Bengisu Bassay (Northampton General Hospital, England); Dermot Dalton (Northern Devon Healthcare NHS Trust, Barnstaple, England); Lauren Fraser (Northwick Park Hospital, London, England); Chris Gough (Nottingham University Hospitals NHS Trust, Nottingham, England); Sharryn Gardner (Ormskirk & District General Hospital, Ormskirk, England); Mark Tighe (University Hospitals Dorset, Dorset, England); Darren Ranasinghe, Simon Birch (Queen Alexandra Hospital, Portsmouth, England); Sharon Hall (Queen Elizabeth Hospital, Woolwich, England); Gareth Patton, Steve Turner (Royal Aberdeen Children’s Hospital, Aberdeen, Scotland); Emily Walton (Royal Alexandra Children’s Hospital, Brighton, England); Julie-Ann Maney, Tom Bourke (Royal Belfast Hospital for Sick Children, Belfast, Northern Ireland); Manish Thakker (Royal Berkshire NHS Foundation Trust, Reading, England); Gisela Robinson, Lizzie Starkey (Royal Derby Hospital, Derby, England); Andrew Appelboam (Royal Devon & Exeter Hospital, Exeter, England); Shye Wei Wong (Royal Free Hospital, London, England); Steven Foster, Louisa Pollock (Royal Hospital for Children, Glasgow, Scotland); Jen Browning (Royal Hospital for Children & Young People, Edinburgh, Scotland); Katherine Potier (Royal Manchester Children’s Hospital, Manchester, England); Kirsty Challen (Royal Preston Hospital, Preston, England); Elizabeth Gilby (Royal United Hospital, Bath, England); Lisa Kehler (Royal Wolverhampton NHS Trust, Wolverhampton, England); Sebastian Gray (Salisbury NHS Foundation Trust, Salisbury, England); Shammi Ramlakhan (Sheffield Children’s NHS Foundation Trust, Sheffield, England); Niall Mullen (South Tyneside & Sunderland NHS Foundation Trust, Sunderland, England); Jane Bayreuther, Katrina Cathie (Southampton Children’s Hospital, Southampton, England); Heather Jarman (St George’s University Hospitals NHS Foundation Trust, London, England); Neil Thompson (St Mary’s Hospital, Imperial College Healthcare NHS Trust, London, England); Ami Parikh (The Royal London Hospital, London, England); Siba Paul (Torbay Hospital, England); Sarah Trippick, Alastair Sutcliffe (University College Hospital London, England); Joanne Mulligan (University Hospital Crosshouse, Kilmarnock, Scotland); Sophie Keers (University Hospital Lewisham, London, England); Jeff Morgan (University Hospital of Wales, Cardiff, Wales) Michelle Jacobs (Watford General Hospital, Watford, England); Mike Linney (Western Sussex Hospitals NHS Trust, Chichester, England); Sarah Wilson (Wexham Park Hospital, Slough, England); Erum Jamall (Whittington Health NHS Trust, London, England).
In addition we thank Mai Baquedano (University Hospitals Bristol and Weston NHS Foundation Trust) for her assistance with construction of the study survey, and data management.
“What is already known on this topic”
• POCT has been explored as an adjunctive tool in clinical decision making for a number of acute conditions
• POCT can potentially help in earlier treatment initiation, improved patient outcomes, patient satisfaction, and patient flow through the emergency department but the evidence for benefit to patients is limited.
• Further larger research studies are required to evaluate the newer POCT in more detail.
“What this study adds”
• Among acute paediatric settings, commonly used POCT include blood gases, urinalysis and blood sugar testing, whilst newer POCT such as inflammatory biomarkers and pathogen identification are less frequently used
• POCT is mostly processed and interpreted by clinical teams, though there is wide variation in their governance
• The most commonly perceived obstacles to the use of POCT are lack of funding, evidence base, and infrastructure to support test performance and quality assurance