Lee J, Shin Y, Choi E, Choi S, Son J, Jung YK, et al. Impact of hospitalization duration before medical emergency team activation: A retrospective cohort study. PLoS One. 2021;16:e0247066.
Maharaj R, Raffaele I, Wendon J. Rapid response systems: a systematic review and meta-analysis. Crit Care. 2015;19:254.
Jones DA, DeVita MA, Bellomo R. Rapid-response teams. N Engl J Med. 2011;365:139–46.
Neale G, Woloshynowych M, Vincent C. Exploring the causes of adverse events in NHS hospital practice. J R Soc Med. 2001;94:322–30.
Lee BY, Hong SB. Rapid response systems in Korea. Acute Crit Care. 2019;34:108–16.
Karpman C, Keegan MT, Jensen JB, Bauer PR, Brown DR, Afessa B. The impact of rapid response team on outcome of patients transferred from the ward to the ICU: a single-center study. Crit Care Med. 2013;41:2284–91.
Jung B, Daurat A, De Jong A, Chanques G, Mahul M, Monnin M, et al. Rapid response team and hospital mortality in hospitalized patients. Intensive Care Med. 2016;42:494–504.
Chang YC, Fang YT, Chen HC, Lin CY, Chang YP, Chen YM, et al. Effect of do-not-resuscitate orders on patients with sepsis in the medical intensive care unit: a retrospective, observational and propensity score-matched study in a tertiary referral hospital in Taiwan. BMJ Open. 2019;9:e029041.
Huang CT, Chuang YC, Tsai YJ, Ko WJ, Yu CJ. High Mortality in Severe Sepsis and Septic Shock Patients with Do-Not-Resuscitate Orders in East Asia. PLoS One. 2016;11:e0159501.
Powell ES, Sauser K, Cheema N, Pirotte MJ, Quattromani E, Avula U, et al. Severe sepsis in do-not-resuscitate patients: intervention and mortality rates. J Emerg Med. 2013;44:742–9.
Physicians. RCo. National Early Warning Score (NEWS) 2. [accessed 11–26, 2021]. Available at: https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2.
Fernando SM, Fox-Robichaud AE, Rochwerg B, Cardinal P, Seely AJE, Perry JJ, et al. Prognostic accuracy of the Hamilton Early Warning Score (HEWS) and the National Early Warning Score 2 (NEWS2) among hospitalized patients assessed by a rapid response team. Crit Care. 2019;23:60.
Vincent JL, Moreno R, Takala J, Willatts S, De Mendonca A, Bruining H, et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med. 1996;22:707–10.
Smith GB, Prytherch DR, Meredith P, Schmidt PE, Featherstone PI. The ability of the National Early Warning Score (NEWS) to discriminate patients at risk of early cardiac arrest, unanticipated intensive care unit admission, and death. Resuscitation. 2013;84:465–70.
Aneman A, Frost SA, Parr MJ, Hillman KM. Characteristics and outcomes of patients admitted to ICU following activation of the medical emergency team: impact of introducing a two-tier response system. Crit Care Med. 2015;43:765–73.
Chan PS, Khalid A, Longmore LS, Berg RA, Kosiborod M, Spertus JA. Hospital-wide code rates and mortality before and after implementation of a rapid response team. Jama. 2008;300:2506–13.
Coventry C, Flabouris A, Sundararajan K, Cramey T. Rapid response team calls to patients with a pre-existing not for resuscitation order. Resuscitation. 2013;84:1035–9.
Group SCCT. Incidence of severe sepsis and septic shock in German intensive care units: the prospective, multicentre INSEP study. Intensive Care Med. 2016;42:1980–9.
Shankar-Hari M, Harrison DA, Rubenfeld GD, Rowan K. Epidemiology of sepsis and septic shock in critical care units: comparison between sepsis-2 and sepsis-3 populations using a national critical care database. Br J Anaesth. 2017;119:626–36.
Huang X, Zhang R, Fan G, Wu D, Lu H, Wang D, et al. Incidence and outcomes of acute respiratory distress syndrome in intensive care units of mainland China: a multicentre prospective longitudinal study. Crit Care. 2020;24:515.
Jentzer JC. Understanding Cardiogenic Shock Severity and Mortality Risk Assessment. Circ Heart Fail. 2020;13:e007568.
Winters BD, Weaver SJ, Pfoh ER, Yang T, Pham JC, Dy SM. Rapid-response systems as a patient safety strategy: a systematic review. Ann Intern Med. 2013;158:417–25.
Howell MD, Ngo L, Folcarelli P, Yang J, Mottley L, Marcantonio ER, et al. Sustained effectiveness of a primary-team-based rapid response system. Crit Care Med. 2012;40:2562–8.
Bannard-Smith J, Lighthall GK, Subbe CP, Durham L, Welch J, Bellomo R, et al. Clinical outcomes of patients seen by Rapid Response Teams: A template for benchmarking international teams. Resuscitation. 2016;107:7–12.
Bellomo R, Goldsmith D, Uchino S, Buckmaster J, Hart G, Opdam H, et al. Prospective controlled trial of effect of medical emergency team on postoperative morbidity and mortality rates. Crit Care Med. 2004;32:916–21.
Bellomo R, Goldsmith D, Uchino S, Buckmaster J, Hart GK, Opdam H, et al. A prospective before-and-after trial of a medical emergency team. Med J Aust. 2003;179:283–7.
Chan PS, Jain R, Nallmothu BK, Berg RA, Sasson C. Rapid Response Teams: A Systematic Review and Meta-analysis. Arch Intern Med. 2010;170:18–26.
Hillman K, Chen J, Cretikos M, Bellomo R, Brown D, Doig G, et al. Introduction of the medical emergency team (MET) system: a cluster-randomised controlled trial. Lancet. 2005;365:2091–7.
Innocenti F, Caldi F, Tassinari I, Meo F, Gandini A, Noto P, et al. SOFA Score prognostic performance among patients admitted to High-Dependency Units. Minerva Anestesiol. 2019;85:1080–8.
Karakike E, Kyriazopoulou E, Tsangaris I, Routsi C, Vincent JL, Giamarellos-Bourboulis EJ. The early change of SOFA score as a prognostic marker of 28-day sepsis mortality: analysis through a derivation and a validation cohort. Crit Care. 2019;23:387.
Vincent JL, de Mendonça A, Cantraine F, Moreno R, Takala J, Suter PM, et al. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on “sepsis-related problems” of the European Society of Intensive Care Medicine. Crit Care Med. 1998;26:1793–800.
Bilben B, Grandal L, Søvik S. National Early Warning Score (NEWS) as an emergency department predictor of disease severity and 90-day survival in the acutely dyspneic patient - a prospective observational study. Scand J Trauma Resusc Emerg Med. 2016;24:80.
Okorie ON, Dellinger P. Lactate: biomarker and potential therapeutic target. Crit Care Clin. 2011;27:299–326.
Park J, Lee YJ, Hong SB, Jeon K, Moon JY, Kim JS, et al. The association between hospital length of stay before rapid response system activation and clinical outcomes: a retrospective multicenter cohort study. Respir Res. 2021;22:60.
Genga KR, Russell JA. Update of Sepsis in the Intensive Care Unit. J Innate Immun. 2017;9:441–55.
Perner A, Gordon AC, De Backer D, Dimopoulos G, Russell JA, Lipman J, et al. Sepsis: frontiers in diagnosis, resuscitation and antibiotic therapy. Intensive Care Med. 2016;42:1958–69.
Vincent JL, Jones G, David S, Olariu E, Cadwell KK. Frequency and mortality of septic shock in Europe and North America: a systematic review and meta-analysis. Crit Care. 2019;23:196.
Xie J, Wang H, Kang Y, Zhou L, Liu Z, Qin B, et al. The Epidemiology of Sepsis in Chinese ICUs: A National Cross-Sectional Survey. Crit Care Med. 2020;48:e209–18.
Shappell C, Snyder A, Edelson DP, Churpek MM. Predictors of In-Hospital Mortality After Rapid Response Team Calls in a 274 Hospital Nationwide Sample. Crit Care Med. 2018;46:1041–8.
Lee J, Ban WH, Kim SW, Kim EY, Han MR, Kim SC. Utilization of a rapid response team and associated outcomes in patients with malignancy. Acute Crit Care. 2020;35:16–23.
Fernando SM, Reardon PM, Bagshaw SM, Scales DC, Murphy K, Shen J, et al. Impact of nighttime Rapid Response Team activation on outcomes of hospitalized patients with acute deterioration. Crit Care. 2018;22:67.